---
title: "Amoxicillin: Uses & Side Effects | HealthAnswers"
description: "Amoxicillin is a penicillin antibiotic for bacterial chest, ear, sinus, dental and urine infections — how to take a full course and what side effects mean."
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# Amoxicillin: Uses & Side Effects | HealthAnswers

Treatments

Amoxicillin is a penicillin antibiotic for bacterial chest, ear, sinus, dental and urine infections — how to take a full course and what side effects mean.

Written by HealthAnswers editorial team Medically reviewed by [HealthAnswers UK doctor review panel](https://healthanswers.co.uk/our-doctors/) Reviewed 3 July 2026

## Quick answer

What is amoxicillin used for? Amoxicillin is a penicillin antibiotic used for bacterial infections such as some chest, ear, sinus, dental and urine infections. Complete the course unless you have an allergic reaction. It does not treat viruses. Diarrhoea is common; a widespread rash or breathing difficulty needs urgent advice.

General UK health information, not a diagnosis. In an emergency call 999 ; for urgent advice use [NHS 111](https://111.nhs.uk/) (GP out-of-hours in Northern Ireland).

On this page 5 sections

## Key facts about amoxicillin

- Amoxicillin is a penicillin antibiotic — always mention any penicillin allergy.
- It only treats bacterial infections, not colds or most sore throats caused by viruses.
- Doses are usually taken three times a day, spaced evenly.
- Finish the prescribed course unless a clinician advises you to stop.
- Seek emergency help for swelling of the face or difficulty breathing.

## What amoxicillin treats

Amoxicillin is a **penicillin antibiotic**. It is used for bacterial infections such as some chest infections, ear infections, [sinusitis](https://healthanswers.co.uk/conditions/sinusitis/), dental infections and urinary tract infections. It is also used with other medicines as part of *H. pylori* treatment for stomach ulcers.

It does **not** work against viruses, so it will not shorten a typical cold or [flu](https://healthanswers.co.uk/conditions/flu/). Prescribers follow guidance to avoid unnecessary antibiotics and reduce resistance.

## How to take amoxicillin

Adults and children have different doses based on age, weight and the infection. Liquid medicine for children should be shaken well; use an oral syringe for accurate measuring.

Space doses evenly — often three times a day. Complete the course even if you feel better, unless you are told to stop because of a reaction.

## Side effects

Common effects include [diarrhoea](https://healthanswers.co.uk/symptoms/diarrhoea/), nausea and mild rash. Contact a GP or pharmacist if diarrhoea is severe or contains blood, or if you become very unwell.

A rash can mean allergy, but not every rash is anaphylaxis. Seek same-day advice for a new widespread rash. For breathing difficulty or facial swelling, call 999.

## Allergy and interactions

People with a penicillin allergy must not take amoxicillin. Cross-reaction with some other [antibiotics](https://healthanswers.co.uk/treatments/antibiotics/) is possible — always list your allergies.

Amoxicillin can interact with medicines such as methotrexate and, rarely, affect warfarin monitoring. Tell the prescriber about all medicines you take. Combined hormonal contraception advice has changed over time — ask a pharmacist if you are unsure whether extra precautions are needed with your specific antibiotic course.

## When to get help during treatment

If symptoms are much worse after 48 hours, you develop a high [fever](https://healthanswers.co.uk/symptoms/high-temperature/) again, or you cannot keep medicine down, contact a GP or call 111. For children, follow NHS guidance on fever and dehydration, and seek urgent help if they are not drinking, are floppy, or are hard to wake.

## ! Important safety information for amoxicillin

A GP, dentist or other prescriber can issue amoxicillin when a bacterial infection is likely. Contact a GP or call **111** if you develop a new rash, severe diarrhoea, or your infection is not improving. Call **999** or go to A&E for anaphylaxis — sudden swelling of the lips, tongue or throat, wheeze, or collapse. Stop the medicine and get emergency help if this happens.

## Common questions about amoxicillin

What if I have a penicillin allergy? If you have a true penicillin allergy, avoid amoxicillin and other penicillins. Tell every healthcare professional and check medicine labels. Many people labelled "allergic" in childhood were never truly allergic — a GP or allergy clinic can sometimes review this safely. Can I take amoxicillin with food or alcohol? Amoxicillin can be taken with or without food. There is no direct dangerous interaction with alcohol, but resting and staying hydrated while unwell is sensible, and alcohol can worsen side effects such as nausea. What should I do if I miss a dose? Take it as soon as you remember unless it is nearly time for the next dose. Do not take two doses together. Try to keep doses evenly spaced across the day. Why must I finish the course? Stopping early can allow bacteria to survive and symptoms to return. If side effects are severe, contact a GP or pharmacist rather than stopping without advice — they may change the antibiotic. Can amoxicillin cause thrush or diarrhoea? Yes. Antibiotics can disturb normal bacteria, leading to diarrhoea or vaginal/oral thrush. Mild diarrhoea is common; severe, bloody or persistent diarrhoea needs medical advice because of the rare risk of C. difficile infection.

## Sources

- [NHS — Amoxicillin](https://www.nhs.uk/medicines/amoxicillin/)
- [NHS — Antibiotics](https://www.nhs.uk/conditions/antibiotics/)

## How we reviewed this page

Medically reviewed by the [HealthAnswers UK doctor review panel](https://healthanswers.co.uk/our-doctors/)

First published 28 June 2026 Medically reviewed 3 July 2026 Next review due 3 July 2029 or sooner if NHS or NICE guidance changes

Written by HealthAnswers editorial team. Published by HealthAnswers (Elite Digital AI Solutions Ltd). [How we review content](https://healthanswers.co.uk/about/how-we-review/) · [Report a problem with this page](mailto:corrections@healthanswers.co.uk?subject=Problem%20with%3A%20Amoxicillin&body=Page%3A%20https%3A%2F%2Fhealthanswers.co.uk%2Ftreatments%2Famoxicillin%2F%0A%0AWhat%20looks%20wrong%20or%20out%20of%20date%3A%0A)
