Diverticulitis — when colon pouches flare

Diverticulosis — presence of diverticula (outpouchings of colon mucosa through muscle wall) — very common — 50% over 60 on colonoscopy.

Diverticulitis — inflammation ± infection of diverticula — painful, febrile illness — 5% with diverticulosis experience this.

Diverticulosis vs diverticulitis

DiverticulosisDiverticulitis
SymptomsUsually nonePain, fever, malaise
TreatmentHigh fibre preventionAntibiotics, sometimes surgery
BleedingPainless PR bleed possibleLess common

Symptoms of diverticulitis

Uncomplicated:

  • constant LLQ pain — left lower abdomen ( sigmoid colon — Western pattern; right-sided in Asia)
  • fever
  • change bowel habit — constipation or diarrhoea
  • nausea
  • tenderness — guarding if severe

Complicated:

  • abscess — persistent fever, mass
  • perforation — peritonitis — rigid abdomen — A&E
  • fistula — colovesical (pneumaturia), colovaginal
  • stricture, obstruction

Diagnosis

Clinical + CT abdomen/pelvis with contrast — gold standard — shows wall thickening, fat stranding, abscess

Blood tests — CRP, WCC elevated

Colonoscopy — not during acute attack — 6 weeks post-recovery if first episode age >40 — exclude cancer

Treatment

Uncomplicated — outpatient

Antibiotics covering gut flora:

  • co-amoxiclav
  • OR ciprofloxacin + metronidazole (if penicillin allergy — local guidance)

Clear liquids → low residue briefly → gradual fibre increase

Paracetamol — avoid NSAIDs early — bleeding risk debate

Some mild cases — antibiotics optional in selected Hinchey 0 — specialist trend — still GP-guided

Complicated — inpatient

  • IV antibiotics
  • CT-guided drainage — abscess >3cm often
  • surgery — Hartmann’s or resection — perforation, failed medical, recurrent

Prevention after recovery

  • high-fibre diet — 30g/day target
  • hydration
  • exercise
  • healthy weight
  • ** nuts/seeds OK** — myth busted

Diverticulitis vs other causes

ConditionClue
AppendicitisRLQ — younger
IBSChronic pain, no fever
Bowel cancerWeight loss, PR bleed — colonoscopy
UTIUrinary symptoms — colovesical fistula rare

See bowel cancer if alarm features.

Left lower pain + fever over 40 — same-day assessment — CT confirms — most home antibiotics, some need surgery.

Common questions about diverticulitis

What are the symptoms of diverticulitis?
Constant abdominal pain — usually left lower quadrant, fever, nausea, constipation or diarrhoea, bloating, blood in stool sometimes. Pain worsens with movement. Unlike diverticulosis which is silent, diverticulitis is painful and systemic illness.
What causes diverticular disease?
Low-fibre Western diet increases colon pressure causing pouches (diverticulosis) in weak spots of colon wall. Faecal matter trapping in pouches can cause inflammation and bacterial infection (diverticulitis). Age, obesity, smoking, and inactivity increase risk.
How is diverticulitis treated?
Uncomplicated — oral antibiotics (co-amoxiclav or ciprofloxacin + metronidazole), paracetamol not NSAIDs initially, clear fluids progressing to low fibre then high fibre after recovery. Complicated — hospital IV antibiotics, CT scan, abscess drainage, surgery if perforated or recurrent severe episodes.
Should I avoid nuts and seeds with diverticular disease?
No — old advice disproven. Nuts, seeds, and popcorn do not cause diverticulitis. When recovered, high-fibre diet reduces recurrence risk. During acute attack, temporary low-fibre diet as advised.
Does diverticulitis lead to colon cancer?
Diverticular disease does not cause cancer but symptoms overlap — colonoscopy recommended after first episode in age-appropriate patients or if alarm features — to exclude malignancy. Repeated episodes may lower threshold for colonoscopy.

Sources

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