Measles — not a harmless childhood rash

Measles is one of the most contagious human diseases — a single case can infect 9 out of 10 unvaccinated people in close contact. Before vaccination, it killed millions globally; MMR vaccine reduced UK cases dramatically — but outbreaks resurge where vaccination rates fall.

It is not trivial — 1 in 15 affected children in the UK develop serious complications.

Symptoms — typical timeline

Day 1 to 3 — prodrome:

Koplik spots — tiny white/grey spots on buccal mucosa (inside cheeks) — pathognomonic, fade as rash appears.

Day 3 to 7 — rash:

  • red-brown maculopapular rash
  • starts behind ears and hairline, spreads face → chest → limbs
  • blanches on pressure (unlike meningococcal rash)
  • fades in order of appearance over 5 to 6 days — may brownish desquamation

How it spreads

Respiratory droplets — cough, sneeze, breathing shared air.

Virus survives in airspace up to 2 hours after infected person leaves room.

Incubation: 10 to 12 days to first symptoms; 14 days to rash.

Who is at risk

  • unvaccinated children and adults
  • infants too young for vaccine (<12 months)
  • immunocompromised — cannot receive live vaccine; rely on herd immunity
  • pregnant women without immunity — miscarriage, prematurity, low birth weight risk

MMR vaccination

Schedule UK:

  • 1 year — MMR dose 1
  • 3 years 4 months — MMR dose 2

Catch-up: anyone missing doses — GP practice or sexual health for adults.

Contraindications to live MMR:

  • pregnancy — avoid pregnancy 1 month after
  • severe immunosuppression
  • anaphylaxis to neomycin or gelatine (rare)

Treatment — supportive

  • paracetamol/ibuprofen — fever, discomfort
  • fluids — prevent dehydration
  • rest
  • no school/work — isolation period
  • vitamin A — WHO recommendation in severe measles in deficiency settings — hospital

Antibiotics — only for secondary bacterial infection.

Complications

ComplicationNotes
Otitis mediaCommon
PneumoniaLeading cause of measles death
DiarrhoeaDehydration risk
Encephalitis1 in 1000 — brain injury/death
SSPEYears later — fatal — very rare

Measles vs other rashes

MeaslesScarlet feverMeningitis
RashHead down, blanchingSandpaper, scarletNon-blanching petechiae
ProdromeCough, conjunctivitisSore throatRapid collapse possible

See scarlet fever guide.

Public health

Notify — measles is notifiable — labs and clinicians report cases.

Contact tracing — unvaccinated contacts may receive MMR within 72 hours post-exposure or immunoglobulin if vulnerable.

Phone ahead before GP visit — do not sit in waiting room with measles.

Measles is almost entirely preventable with two MMR doses — resurgence reflects vaccine gaps, not virus weakening. If unvaccinated — catch up today.

Common questions about measles

What are the first signs of measles?
High fever, runny nose, cough, red sore eyes (conjunctivitis), and small grey-white Koplik spots on inside of cheeks — rash follows 2 to 4 days later starting on face and spreading downward over 3 to 4 days.
How long is measles contagious?
From 4 days before rash appears until 4 days after rash onset — roughly 8 days total. Stay home from school, work, and public places during this period. Highly contagious to unvaccinated people in same room.
Can adults get measles?
Yes — often more severe than children — higher hospitalisation and complication rates. Adults born before 1970 may have natural immunity; those without two MMR doses or confirmed immunity should vaccinate if not pregnant or immunosuppressed.
Is there a treatment for measles?
No specific antiviral — supportive care with paracetamol or ibuprofen, fluids, rest. Vitamin A given in some severe cases in hospital — deficiency worsens outcomes. Antibiotics only if bacterial complication like pneumonia develops.
How effective is the MMR vaccine?
One dose protects about 93% — two doses about 97%. MMR also covers mumps and rubella. Safe for most people — myths linking MMR to autism disproved repeatedly by large studies.
What complications can measles cause?
Ear infection, pneumonia, diarrhoea, fits (febrile convulsions), encephalitis (brain inflammation — rare, can be fatal or cause brain damage), subacute sclerosing panencephalitis (very rare late complication years later).

Sources

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